Mouse Podocyte

Mouse Podocyte
Model: PCKDM01
Species: Mus Musculus
Catalog Number: PCKDM01
Availability: In Stock
Price: $749.00
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Species: Mus Musculus Catalog Number: PCKDM01
Cell Number: ~5x105 Storage/Shipping: Room Temp

 

Introduction:

Podocytes are a group of terminally differentiated cells located in the outer aspect of glomerular basement membrane (GBM). They have special morphology with multiple long foot processes that cover the entire outer surface of the capillary of glomerulus and form a tight barrier to filter the blood and form the initial urine1. These cells are very important to maintain the normal function of the kidney and podocyte injury could result in massive proteinuria and eventually kidney failure2, 3.

PrimCells is proud to isolate and provide the primary cultures of podocytes from mouse, rat and non-human primate to the research community. These cells have been isolated using traditional sieving method and are confirmed to express typical podocyte markers such as Nephrin, Synaptopodin and WT1 and can be a valuable tool to study the function of genes in nephrology and/or drug induced toxicity in glomerular injury.

Figure 1 | Mouse podocytes are positive for Nephrin, Synaptopodin and WT1

Click here to download PDF datasheet

Click here to download PDF datasheet

For additional information regarding the product and technical questions, please contact Supports@PrimCells.com.  You are guaranteed to receive a response within 24hrs from one of our scientists.

1. Pavenstadt, H., Kriz, W. & Kretzler, M. Cell biology of the glomerular podocyte. Physiol Rev 83, 253-307 (2003).
2. Pagtalunan, M.E. et al. Podocyte loss and progressive glomerular injury in type II diabetes. J Clin Invest 99, 342-348 (1997).
3. Wolf, G., Chen, S. & Ziyadeh, F.N. From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54, 1626-1634 (2005).
 

This product is intended for laboratory research purposes only. It is not intended for use in humans. While PrimCells uses reasonable efforts to include accurate and up-to-date information on this product sheet, PrimCells makes no warranties or representations as to its accuracy. Citations from scientific literature and patents are provided for informational purposes only. PrimCells does not warrant that such information has been confirmed to be accurate.

This product is sent with the condition that you are responsible for its safe storage, handling, and use. PrimCells is not liable for any damages or injuries arising from receipt and/or use of this product. While reasonable effort is made to insure authenticity and reliability of strains on deposit, PrimCells is not liable for damages arising from the misidentification or misrepresentation of cultures.
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